Active Projects
K01: Classification of Ankle Osteoarthritis Severity from Weightbearing Computed Tomography Using Statistical Shape Modeling and Machine Learning
K01AR080221-01 - A. Lenz (PI)
National Institutes of Health (NIH) - National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
07/01/2022-06/30/2027 - $666,900 total costs
Goals: A 3D computational study to characterize ankle joint complex osteoarthritis by quantifying anatomical shape variation through statistical shape modeling of the tibiotalar and subtalar joints.
R01: Post-Surgical Form and Function of Planovalgus Foot Deformities in Patients with Cerebral Palsy
R01AR083490 - A. Lenz (PI)
National Institutes of Health (NIH) - National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
05/15/2024-04/30/2029 - $3,265,005 total costs
Goals: Standardization of foot and ankle local coordinate systems and investigation of adult patients with cerebral palsy that have a history of foot deformity, whether it was surgically reconstructed or not in adolescence. The long-term goal is to better understand form and function for improved foot function into adulthood.
Shriners Clinical Research Grant: Weightbearing CT Imaging: Applications to Pediatric Flatfoot Deformity
K. Kruger (PI), A. Lenz (co-I)
01/01/2025-12/31/2028 - $2,192,691
Goals: Limitations of static weight-bearing radiographs have been unable describe relationships between joint alignment and functional movement. Our team’s long-term objective is to provide a more comprehensive assessment of the 3D variability of foot structure in children. Translation of WBCT to pediatric applications would allow for better treatment planning in children with these complex foot disorders.
College of Health Research Incentive Seed Grant: Towards A New Vision For Footwear Research And Health-Related Applications
K. Takahashi (PI), A. Lenz (co-PI)
05/01/2024-04/30/2025 - $27,500
Goals: Evaluate various carbon fiber insoles during human locomotion to assess energy cost savings and kinematic compensations compared to barefoot walking. Outcomes of this study will identify optimal carbon fiber stiffnesses for insoles to aid in walking efficiencies without causing compromised foot function.
UOC Pediatric Orthopaedic Research Grant Program: Characterization of Foot Morphology in Genetic Subtypes of Charcot Marie Tooth Disease
A. Lenz (PI)
11/20/2023–11/19/2025 - $80,000
Goals: Evaluate using 3D statistical shape modeling the influence of morphology on various genetic subtypes of Charcot Marie Tooth. Using weightbearing computed tomography, patient specific 3D models are generated and computational studies are conducted to quantify shape differences.
Completed Projects
Shriners Clinical Research Grant: Shriners Clinical Research Grant: Weightbearing CT Imaging: Applications to Pediatric Flatfoot Deformity
K. Kruger (PI), A. Lenz (co-PI)
01/01/2020-12/31/2023 - $683,349 total costs
Goals: Develop a standardized protocol for assessment of tibiotalar and subtalar kinematics using biplane fluoroscopy and to assess the long-term effectiveness of surgical correction for pes planovalgus deformity.
LS-Peery Foundation Grant: Robotic Simulator for Replicating Foot and Ankle Kinematics and Kinetics to Evaluate Post-Surgical Compensations
A. Lenz (PI)
11/01/2022-12/31/2023 - $100,000
Goals: Created an adaptable high-speed robotic joint simulator to evaluate the effects of surgical interventions surgery on hindfoot kinematic compensations.
UOC Pediatric Orthopaedic Research Grant Program: Characterization of Foot and Ankle Morphology in Pediatric Patients with Cerebral Palsy
A. Lenz (PI)
01/01/2022–12/31/2023 - $80,000
Goals: Develop computational methods and statistical shape models to evaluate the 3D shape of the foot and ankle morphology in pediatric patients with cerebral palsy.
School of Medicine Research Incentive Seed Grant: Evaluation of 3D Morphology in Patients with Charcot-Marie-Tooth For Improved Surgical Planning
A. Lenz (PI)
04/01/2022–03/31/2023 - $50,000
Goals: Develop statistical shape models to quantify talar morphology and assess talar neck cam lesions in patients with Charcot-Marie-Tooth for surgical treatment planning.
Paragon 28 Inc.: Subtalar Joint Range of Motion Robotic Cadaver Testing
A. Lenz (PI)
03/01/2022–03/31/2023 - $69,870.60
Goals: Develop proof of concept methods to determine greatest range of motion (ROM) of the subtalar joint (STJ) in a variety of different loaded and unloaded configurations using robotic manipulation.
Stryker/ORS Women’s Research Fellowship: Advancing Total Ankle Replacement Through Morphometric and Kinematic Analyses
A. Lenz (PI), A. Anderson (Sponsor)
04/01/2019–3/31/2020 - $50,000
Goals: Utilize statistical shape modeling to compute healthy variation in tibiotalar morphometrics and quantify tibiotalar and subtalar kinematics following total ankle replacement using dual-fluoroscopy.